Xuefeng Hu
Affiliation
Postdoctoral Fellow
Email: xuefeng.hu@uottawa.ca
Research interests
Environment, Nutrition & Health
Cardiovascular disease
Nutrients and environmental contaminants
Systematic reviews and meta-analysis
Survey data and linked data analysis
Statistics Canada data
Bio
I have a background in medicine, public health nutrition, and health economics, and have been trained as an epidemiologist in evidence-based medicine and environmental health. My postdoctoral research focuses on diet, environmental exposures, and their associations with chronic disease among Canadians, including Indigenous people. I am familiar with most of the health-related national representative Canadian databases, including the linked database between census, dietary and environmental factors, and administrative data, e.g. discharge abstract data and vital statistics.
Research project
Mercury exposure, hypertension, cardiovascular disease, and mortality
Selenium’s protective effect on stroke
Chinese dietary pattern and health
Global selenium biomarker database
Publications
Peer-reviewed journal publications:
Hu XF, Chan HM. Seafood consumption and its contribution to nutrients intake among canadians in 2004 and 2015. Nutrients 2021;13:1–11. doi:10.3390/nu13010077
Chan HM, Hu XF, Cheung JS, et al. Cohort profile: Health effects monitoring programme in Ndil?, Dettah and Yellowknife (YKHEMP). BMJ Open 2020;10:1–9. doi:10.1136/bmjopen-2020-038507
Cheung JSJ, Hu XF, Parajuli RP, et al. Health risk assessment of arsenic exposure among the residents in Ndilǫ, Dettah, and Yellowknife, Northwest Territories, Canada. Int J Hyg Environ Health 2020;230:113623. doi:10.1016/j.ijheh.2020.113623
Feng L, Zhang C, Liu H, et al. Impact of low-level mercury exposure on intelligence quotient in children via rice consumption. Ecotoxicol Environ Saf 2020;202:110870. doi:10.1016/j.ecoenv.2020.110870
Hu XF, Stranges S, Chan LHM, et al. Circulating Selenium Concentration Is Inversely Associated With the Prevalence of Stroke: Results From the Canadian Health Measures Survey and the National Health and Nutrition Examination Survey. J Am Heart Assoc 2019;8:e012290. doi:10.1161/JAHA.119.012290
Juric A, Singh K, Hu XF, et al. Exposure to triclosan among the Canadian population: Results of the Canadian Health Measures Survey (2009–2013). Environ Int 2019;123:29–38. doi:10.1016/j.envint.2018.11.029
Kenny T, Hu XF, Jamieson JA, et al. Potential impact of restricted caribou (Rangifer tarandus) consumption on anemia prevalence among Inuit adults in northern Canada. BMC Nutr 2019;5.
Hu XF, Chan HM. Factors associated with the blood and urinary selenium concentrations in the Canadian population: Results of the Canadian Health Measures Survey (2007–2011). Int J Hyg Environ Health 2018;221:1023–31. doi:10.1016/j.ijheh.2018.07.001
Hu XF, Kenny T, Chan HM. Inuit Country Food Diet Pattern Is Associated with Lower Risk of Coronary Heart Disease. J Acad Nutr Diet 2018;118:1237–48. doi:10.1016/j.jand.2018.02.004
Hu XF, Singh K, Chan HM. Mercury Exposure , Blood Pressure , and Hypertension : A Systematic Review and Dose – response Meta-analysis. Enviromental Heal Perspect 2018;126:076002.https://doi.org/10.1289/EHP2863
Hu XF, Singh K, Kenny TA, et al. Prevalence of heart attack and stroke and associated risk factors among Inuit in Canada: A comparison with the general Canadian population. Int J Hyg Environ Health Published Online First: 2018. doi:10.1016/j.ijheh.2018.12.003
Marushka L, Hu X, Batal M, et al. The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba , Canada : A Difference in Difference Analysis. Int J Environ Reserch Public Heal 2018;15:539. doi:10.3390/ijerph15030539
Hu XF, Han X, Yang Z, et al. The impact of broadened diagnostic criteria on the prevalence of hypertension, hyperlipidemia and diabetes mellitus in China. Chinese J Prev Med 2017;51:369–77.
Hu XF, Sharin T, Chan MH. Dietary and blood selenium are inversely associated with the prevalence of stroke among Inuit in Canada. J Trace Elem Med Biol 2017;44:322–30. doi:10.1016/j.jtemb.2017.09.007
Hu XF, Young K, Chan HM. Estimating cardiovascular disease incidence from prevalence: a spreadsheet based model. BMC Med Res Methodol Published Online First: 2017. doi:10.1186/s12874-016-0288-y
Hu XF, Laird BD, Chan HM. Mercury diminishes the cardiovascular protective effect of omega-3 polyunsaturated fatty acids in the modern diet of Inuit in Canada. Environ Res 2017;152:470–7. doi:10.1016/j.envres.2016.06.001
Yang Z, Liu L, Mao C, et al. Chemotherapy with cetuximab versus chemotherapy alone for chemotherapy-naive advanced non-small cell lung cancer ( Review ) SUMMARY OF FINDINGS FOR THE MAIN COMPARISON. Cochrane Database Syst Rev Published Online First: 2014. doi:10.1002/14651858.CD009948.pub2.www.cochranelibrary.com
Zhong B, Liu T, Chiu HF, et al. Prevalence of psychological symptoms in contemporary Chinese rural-to-urban migrant workers: an exploratory meta-analysis of observational studies using the SCL-90-R. Soc Psychiatry Psychiatr Epidemiol 2013;48:1569–81. doi:10.1007/s00127-013-0672-4
Mao C, Yang Z, Hu X, et al. PIK3CA exon 20 mutations as a potential biomarker for resistance to anti-EGFR monoclonal antibodies in KRAS wild-type metastatic colorectal cancer: a systematic review and meta-analysis. Ann Oncol 2012;23:1518–25. doi:10.1093/annonc/mdr464
Yang Z, Shen W, Hu X, et al. EGFR gene copy number as a predictive biomarker for the treatment of metastatic colorectal cancer with anti-EGFR monoclonal antibodies: a meta-analysis. J Hematol Oncol 2012;5:52. doi:10.1186/1756-8722-5-52
Hu X, Li Y, Wang J, et al. Safety assessment of hemp seed oil and its antioxidant function in serum. (In Chinese). Chinese J Food Hyg 2008;20:388–92.
Li Y, Yang R, Hu X, et al. Initial study of Hemp seeds protein on antifatigue and the immunomodulation effects in mice. (In Chinese). J Hyg Res 2008;37:175–8.
Yang R, Pei X, Zhang Z, et al. Study on the Radioprotective Effect of Marine Protein Peptide Combined with or without Ganoderma lucidum Polysaccharides. (In Chinese). Food Ferment Ind 2008;5:1–5.
Book Chapters:
Hu XF & Chan HM. (2020) Selenium and human health. In: Prasad A. and Brewer G. (eds.): Micronutrients in Human Health. Elsevier.
Hu XF & Tang JL. (2016) How to understand an article on economic analysis of clinical practice. In: Tang JL, Glasziou P. (eds.): Essentials in Evidence-based Medicine (2nd Edition). Beijing: Peking University Medical Press, pp. 208-220.
Patents:
“A method and device for cholesterol screening.” 20180409000895910. Inventors: Jinling Tang; Xuefeng Hu.
Presentations:
Hu XF, Stranges S, Chan HM. Whole blood selenium concentration is negatively associated with the prevalence of Stroke -- results from CHMS 2007-2011 and NHANES 2011-2012. AHA EPI | Lifestyle 2019 Scientific Sessions, March 6, in Houston, Texas, USA
Hu XF, Zhang R, Chan HM. Dietary patterns in China: a systematic review. Nutrition 2018, June 10, 2018, in Boston, MA, USA
Hu XF, Jaquemet G, Chan HM. Global status of dietary selenium intake and selenium biomarkers. Nutrition 2018, June 10, 2018, in Boston, MA, USA
Hu XF, Singh K, Chan HM. A meta-epidemiological study to explore dose-response and threshold for mercury and blood pressure in humans. ICMGP 2017, July 17, 2017, in Providence, Rhode Island, USA.
Hu XF, Eccles K, Chan HM. Selenium protects against the toxic effects of mercury on cardiovascular health among Inuit in Canada. ICMGP 2017, July 17, 2017, in Providence, Rhode Island, USA.
Hu XF, Chan HM. Inuit Health Survey findings in the ISR -- updates with a focus on beluga whales. Beluga Summit, February 23, 2016, Inuvik, Canada.
Hu XF, Laird B, Chan HM. Mercury diminishes the beneficial effect of omega-3 fatty acids on myocardial infarction among Inuit in Canada. NCP 21st Results Workshop, December 8 2015, Vancouver, Canada.
Hu XF, Eccles K, Chan HM. Impact of the “National Action Plan against Air Pollution 2013- 2017” on cardiovascular disease burden in China. The 27th Conference of International Society of Environmental Epidemiologist, August 29, 2014, Sao Paulo, Brazil.
Hu XF, Kim JH, Tang JL. Using cross-sectional data to model the impact of a vascular checking program 10 years later. The Academic Forum for Ph.D. Candidates from the Mainland, Taiwan, Hong Kong, and Macao, September 10, 2012, Macao, China.
Hu XF, Stevens S, Stevens R. Validation studies within QResearch and CPRD. NIHR School for Primary Care Research (NSPCR) Research Showcase, June 29, 2012, London, UK.
Hu XF, Kim JH, Tang JL. How to select high-risk patients through vascular checking in China, an example for the South Asia countries? 3rd Asia Pacific Primary Care research Conference, December 3, 2011, Kuala Lumpur, Malaysia.
Hu XF, Kim JH, Tang JL. Is there a universal age scope for vascular checking program? International Conference on Global Health and Public Health Education, October 14 2011, Hong Kong, China.
Hu XF, Kim JH, Tang JL. The suitable cholesterol screening age scope for Asian countries. The 42nd APACPH Conference, November 26, 2010, Bali, Indonesia.
Hu XF, Liu GG, Fan M. The selection effect of Chinese Famine 1959-61. The 42nd APACPH Conference, November 25 2010, Bali, Indonesia.